Ketamine Therapy
Overview:
Ketamine therapy is a breakthrough mental health treatment that offers rapid relief for conditions like depression, anxiety, PTSD, and chronic pain—especially in cases where traditional medications have failed. Originally used as an anesthetic, ketamine works differently by targeting the glutamate system and promoting new neural connections in the brain.
By acting on NMDA receptors, ketamine helps reset brain communication pathways, often bringing noticeable symptom relief within hours or days. It’s available in several forms, including IV infusions, intramuscular injections, oral lozenges, and Spravato® nasal spray, all administered in a safe, supervised setting.
Unlike standard antidepressants, ketamine doesn’t require weeks to take effect and may also reduce suicidal thoughts quickly. With its fast-acting and restorative properties, ketamine is becoming a trusted option for those seeking a new path forward in mental health care.
Fast Acting Treatment
Benefits of Ketamine:
- Rapid Relief of Symptoms
- Unlike traditional antidepressants that can take weeks to work, ketamine often provides noticeable relief within hours or days—especially helpful for those experiencing severe symptoms or suicidal thoughts.
- Reduces Suicidal Thinking
- Ketamine is one of the few treatments that can rapidly reduce suicidal ideation, making it a potentially life-saving intervention for those in crisis.
- Promotes Brain Healing and Neuroplasticity
- By acting on the glutamate system, ketamine supports the growth of new neural connections, helping the brain “reset” and better regulate mood over time.
Accepting Most Major Insurance Companies:
Ketamine offers fast, life-changing relief.
How Does It Work?
Ketamine therapy works by targeting the brain’s glutamate system, which plays a key role in mood, learning, and memory. Unlike traditional antidepressants that can take weeks, ketamine acts quickly—often within hours—by restoring healthy brain connections and boosting neuroplasticity. This helps “reset” areas of the brain affected by depression, making it easier to manage thoughts, emotions, and stress. It's fast, effective, and offers real hope for those who haven’t found relief elsewhere.
Don't Take our Word For It.
Third Party Studies:
- Rapid Antidepressant Effects in Treatment-Resistant Depression – National Library of Medicine
- A single IV dose of ketamine led to significant symptom improvement within hours in patients with depression.
- Sustained Improvement Over One Month – National Library of Medicine
- Ketamine showed rapid and sustained antidepressant effects over a one-month period, especially in patients with chronic depression.
- Comparison with Electroconvulsive Therapy (ECT) – Harvard.edu
- Ketamine was nearly as effective as ECT in treating depression, with fewer cognitive side effects and quicker onset.
- Reduction in Suicidal Ideation – National Library of Medicine
- Ketamine produced rapid reduction in suicidal thoughts in patients with treatment-resistant depression, within hours of infusion.
- Adjunctive Therapy Benefits – National Library of Medicine
- Ketamine as an add-on to existing therapy significantly reduced depressive symptoms in patients unresponsive to antidepressants.
- Real-World Effectiveness – National Library of Medicine
- Multiple real-world clinical studies confirmed ketamine’s safety and effectiveness in treatment-resistant depression.
- Efficacy in Bipolar Depression – National Library of Medicine
- Ketamine infusions improved depressive symptoms in both unipolar and bipolar depression patients, expanding its treatment potential.
- Rapid Reduction in Depression and Anxiety – National Library of Medicine
- Ketamine provided significant symptom relief in both depression and anxiety within 40 minutes, with benefits lasting several days.
- Sustained Antidepressant Effects – National library of medicine
- Single sub-anesthetic doses of ketamine induced rapid, robust, and long-lasting antidepressant effects in patients with major depression.
- Mechanism of Action and Safety Profile – National Library of Medicine
- This comprehensive review explains how ketamine modulates glutamate and demonstrates a favorable side-effect profile.
What Results Can You Expect?
Ketamine therapy can lead to rapid and noticeable relief from depression, often within hours or days. Many patients report reduced sadness, anxiety, and suicidal thoughts after just a few sessions. It helps improve mood, motivation, and mental clarity by rebuilding healthy brain connections. Results vary, but for those with treatment-resistant depression, ketamine offers a new path forward—especially when other treatments haven’t worked. Most patients complete a short series of sessions, followed by long-lasting improvement.
What to Expect During Treatment?
When starting ketamine therapy for depression, you’ll first have a medical evaluation to ensure it's right for you. Treatment usually takes place in a calm, supervised setting. During each session, you may feel relaxed, dreamlike, or emotionally open. Sessions last about 40 minutes to an hour, depending on the method. Most people notice mood improvement after a few treatments. You’ll stay alert, and there’s no sedation or downtime. The experience is safe, controlled, and guided by trained professionals focused on your comfort and care.
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The Different Kinds of Ketamine Treatments
Spravato® (esketamine nasal spray) is an FDA-approved treatment for adults with treatment-resistant depression and depression with suicidal thoughts. Unlike traditional antidepressants, Spravato works quickly by targeting the glutamate system, helping restore connections in the brain. It’s taken in a clinic under medical supervision, typically twice a week to start. Patients remain onsite for at least two hours post-dose for monitoring. Spravato is often used alongside an oral antidepressant and has shown rapid symptom relief, sometimes within 24 hours. It’s a safe, powerful option when standard treatments haven’t worked. Learn More.
Intramuscular (IM) Ketamine Injections are a fast and effective treatment for depression, anxiety, PTSD, and more. Ketamine is injected into a muscle—usually the arm or thigh—under medical supervision in a calm clinic setting. The effects begin within minutes, offering rapid relief for those struggling with treatment-resistant depression. Sessions last about an hour, and many patients report feeling lighter, more hopeful, and emotionally reset. IM ketamine works by stimulating the glutamate system and promoting healthy brain connections. It’s safe, convenient, and a powerful option for people needing fast, non-oral treatment. Learn More.
IV Ketamine Infusion Therapy is a fast-acting treatment for depression, anxiety, PTSD, and other mood disorders. It’s especially effective for treatment-resistant depression, where other medications have failed. Ketamine is delivered through an IV in a calm, supervised medical setting. Each session typically lasts about 40 to 60 minutes. Many patients report relief within hours or days, with benefits that can last weeks. The therapy works by boosting glutamate activity and helping the brain form new connections. It’s safe, well-tolerated, and offers real hope for those needing rapid and effective relief from emotional suffering. Learn More.
Oral Ketamine (Lozenges or Capsules) offers a convenient, at-home option for ongoing treatment of depression, anxiety, PTSD, and more. Prescribed after an in-clinic assessment, oral ketamine is absorbed through the digestive system or mouth lining. Though slower-acting than IV or IM, it can still provide meaningful relief, especially when used as maintenance therapy. It promotes brain healing by activating the glutamate system and encouraging new neural connections. Taken under professional guidance, oral ketamine is safe, easy to use, and helps extend the benefits of initial in-clinic treatments over time. Learn More.
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